Some setup is required specifically to use MSAG Validation in Customer Care, and some is required in general – whether you use it in Customer Care or Desktop Client.
To use in Customer Care:
Enable MSAG validation in Customer Care – This is done via MANAGE > Settings > General > Enable MSAG Validation.

Set up user roles and permissions - Users responsible for MSAG validation in Customer Care must be assigned a role with Manage Service Address permission in the Security web module.
The following is required regardless of where you use MSAG validation:
Add an MSAG validation node in Config Console – This must be completed by an authorized IDI associate on your behalf.
Manage MSAG providers – This is done via Admin Console Data Management as described in Desktop Online Help.
Upload MSAG files - MSAG providers generate the addresses that are loaded into the MSAG table. Each MSAG provider you use has a set of records containing location information for the respective Service Addresses. Uploading these files is done via Desktop Client Applications > BackOffice Management > MSAG Management > MSAG File Upload. See Desktop Online Help.